Nociceptive brain activity as a measure of analgesic efficacy in infants
نویسندگان
چکیده
منابع مشابه
The relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants
Measuring infant pain is complicated by their inability to describe the experience. While nociceptive brain activity, reflex withdrawal and facial grimacing have been characterised, the relationship between these activity patterns has not been examined. As cortical and spinally mediated activity is developmentally regulated, it cannot be assumed that they are predictive of one another in the im...
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15 صفحه اولNociceptive Cortical Activity Is Dissociated from Nociceptive Behavior in Newborn Human Infants under Stress
Newborn infants display strong nociceptive behavior in response to tissue damaging stimuli, and this is accompanied by nociceptive activity generated in subcortical and cortical areas of the brain [1, 2]. In the absence of verbal report, these nociceptive responses are used as measures of pain sensation in newborn humans, as they are in animals [3, 4]. However, many infants are raised in a phys...
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ژورنال
عنوان ژورنال: Science Translational Medicine
سال: 2017
ISSN: 1946-6234,1946-6242
DOI: 10.1126/scitranslmed.aah6122